Search Result
Results for "
<i>Isodon excisoides<_i> (Sun ex C. H. Hu) H. Hara
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
2
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N3181
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Others
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Others
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Nodosin is a diterpenoid isolated from Isodon trichocarpus Kudo and I. Japonicus HARA .
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- HY-101245
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Sun-1165; Pilzicainide(hydrochloride)
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Pilsicainide hydrochloride (SUN-1165) is an orally active sodium channel blocker and potent class Ic antiarrhythmic agent .
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- HY-101493
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- HY-147681
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FGFR
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Neurological Disease
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SUN13837 is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. SUN13837 shows neuroprotective activity. SUN13837 can be used for neurodegenerative diseases research .
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- HY-133715
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Sun 1165 free base; Pilzicainide
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Sodium Channel
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Cardiovascular Disease
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Pilsicainide (SUN 1165 free acid) is a potent sodium channel blocker and potent class Ic antiarrhythmic agent .
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- HY-U00084
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- HY-RS14029
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Small Interfering RNA (siRNA)
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Others
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SUN1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SUN1 Human Pre-designed siRNA Set A
SUN1 Human Pre-designed siRNA Set A
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- HY-RS14030
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Small Interfering RNA (siRNA)
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Others
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SUN2 Human Pre-designed siRNA Set A contains three designed siRNAs for SUN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SUN2 Human Pre-designed siRNA Set A
SUN2 Human Pre-designed siRNA Set A
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- HY-RS14031
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Small Interfering RNA (siRNA)
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Others
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SUN3 Human Pre-designed siRNA Set A contains three designed siRNAs for SUN3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SUN3 Human Pre-designed siRNA Set A
SUN3 Human Pre-designed siRNA Set A
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- HY-RS14032
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Small Interfering RNA (siRNA)
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Others
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SUN5 Human Pre-designed siRNA Set A contains three designed siRNAs for SUN5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SUN5 Human Pre-designed siRNA Set A
SUN5 Human Pre-designed siRNA Set A
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- HY-N3321
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Others
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Others
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Maoyerabdosin is a compound isolated from the leaves of Isodon japonica .
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-
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- HY-N3400
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Others
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Others
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Lasiodonin is a diterpenoids compound isolated from Isodon lasiocarpus .
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-
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- HY-103302
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CGRP Receptor
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Endocrinology
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SUN B8155, a non-peptide agonist of calcitonin (CT) receptor, selectively mimics the biological actions of calcitonin. Calcitonin, a 32-amino acid peptide hormone secreted mainly from the thyroid gland, plays an important role in maintaining bone homeostasis .
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- HY-U00367
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- HY-N3798
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Bacterial
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Infection
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Effusanin A is a natural product that can be found in Isodon rugosus. Effusanin A exhibits DNA-damaging and antibacterial activities .
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- HY-N1258
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Others
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Others
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Sculponeatin N is a ent-kaurane diterpene derivative compound isolated from the plant Isodon sculponeata .
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- HY-N10643
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Rabdoternin H
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Others
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Others
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Lushanrubescensin H (Rabdoternin H) is an ent-Kaurane diterpenoid from Isodon ternifolius aboveground part .
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- HY-N9017
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Others
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Others
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12E,14-Labdadien-20,8β-olide, a labdane diterpenoid, is a natural product that can be isolated from the rhizomes of Isodon yuennanensis .
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- HY-N10078
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Others
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Others
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Gardenin D is a natural product. Gardenin D can be isolated from the leaves of Isodon rubescens var. lushiensis .
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- HY-133223
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Others
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Cancer
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Hispidanin B is a natural product that can be extracted from the rhizomes of Isodon hispida. Hispidanin B has cytotoxic activities against cancer cells .
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- HY-N1256
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Others
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Others
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Sculponeatic acid is a new A-ring contracted oleanane triterpene that can be isolated from Isodon sculponeata .
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- HY-N11050
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Apoptosis
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Cancer
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Xerophilusin B, an anticancer agent isolated from Isodon xerophilus, exhibits antiproliferative effects on esophageal squamous cell carcinoma (ESCC) cell lines, induces G2/M cell cycle arrest, and mediates apoptosis .
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- HY-N9983
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Others
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Cancer
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Effusanin E is a diterpenoid. Effusanin E, a 7α, 20-Epoxy-ent-kauranoid, can be obtained from Isodon parvifolius. Effusanin E can be used for the research of cancer .
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- HY-A0067
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Benzophenone 3
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RAR/RXR
Autophagy
Apoptosis
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Neurological Disease
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Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .
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- HY-N8646
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Others
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Cancer
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Isodonal is a N-pentane diterpene compound with potential cytotoxic, antitumor, inhibitory oxidative phosphorylation and antiingestion activities. Isodonal can be isolated from the leaves of Isodon wikstroemioides and is used in the study of gastrointestinal diseases, anti-tumor and anti-inflammatory .
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- HY-153488
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Ras
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Cancer
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ISIS-2503 is a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression
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- HY-153488A
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Ras
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Cancer
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ISIS-2503 sodium is a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression
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- HY-N7521
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Procyanidine C2
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Others
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Others
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Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .
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- HY-N2969
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Others
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Others
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Bulleyanin is a compound isolated from isodon species (Labiatae) .
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- HY-123467
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Others
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Others
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Lasiokaurin is a diterpenoid compound isolated from Isodon lasiocarpus .
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- HY-N1062
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Xerophilusin G is a diterpenoid that can be isolated from Isodon enanderianus .
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- HY-N9930
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Fungal
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Infection
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Effusanin B (Compound 3) is a diterpenoid can be isolated from Rabdosia effusa (Maxim.) Hara. Effusanin B (Compound 3) has antifungal activity .
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- HY-N3322
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Others
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Others
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Maoecrystal B is a diterpenoids compound isolated from the leaves of Isodon eriocalyx var. laxiflora .
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- HY-N11049
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Others
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Others
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Xerophilusin A, a ent-kaurane diterpenoid, can be isolated from the aerial parts of Isodon enanderianus .
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- HY-N2504
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- HY-N12746
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Others
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Others
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Lasiokaurinin (compound 18) is an n-pentane diterpene isolated from the aerial parts of Isodon adenolomus .
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- HY-N7463
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Others
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Others
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Serrin A is an immunosuppressive ent-kaurene diterpenoid. Serrin A can be isolated from the aerial parts of Isodon serra .
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- HY-15871
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Ras
Apoptosis
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Cancer
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GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM.
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- HY-N1871
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4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol is a phenylethanoid isolated from the stem bark of Syringa reticulate (Bl.) Hara (Oleaceae) with expectorant and antiasthmatic activity .
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- HY-100876
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Ras
Apoptosis
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Cancer
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GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.
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- HY-N3428
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Others
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Cancer
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Kamebanin can be isolated from the leaves of Isodon weisiensis C. Y. Wu. Kamebanin has anti-proliferative activity and can be used in cancer research .
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- HY-30151
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Methoxsalen
Maximum Cited Publications
12 Publications Verification
8-Methoxypsoralen; Xanthotoxin; 8-MOP
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Cytochrome P450
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Inflammation/Immunology
Cancer
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Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
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- HY-B0928S
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Homomenthyl salicylate-d4
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Isotope-Labeled Compounds
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Others
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Homosalate-d4 is the deuterium labeled Homosalate. Homosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage.
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- HY-B0928
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Homomenthyl salicylate
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Biochemical Assay Reagents
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Others
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Homosalate (Homomenthyl salicylate) is an organic compound used as a sunscreen to filter UV rays and protect the skin from sun damage. Homosalate has anti-inflammatory activity .
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- HY-135737
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Others
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Others
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Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .
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- HY-N2303
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Eriocalyxin B is an ent-Kaurene diterpenoid isolated from Chinese herb Isodon eriocalyx. Eriocalyxin B has anti-cancer and anti-infammatory activities. Eriocalyxin B induces cell apoptosis .
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- HY-N11544
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NO Synthase
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Inflammation/Immunology
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Inflexuside B, an abietane diterpenoid, can be isolated from the aerial parts of Isodon inflexus. Inflexuside B strongly inhibits lipopolysaccharide (LPS)-activated NO Synthase in RAW264.7 macrophages .
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- HY-N11548
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NO Synthase
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Inflammation/Immunology
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Inflexuside A, an abietane diterpenoid, can be isolated from the aerial parts of Isodon inflexus. Inflexuside B strongly inhibits lipopolysaccharide (LPS)-activated NO production (NO Synthase) in RAW264.7 macrophages .
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- HY-N3828
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Apoptosis
ERK
JNK
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Cancer
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epi-Eriocalyxin A (Epieriocalyxin A), a diterpenoid isolated from Isodon eriocalyx, induces colon cancer apoptosis. epi-Eriocalyxin A also inhibits ERK1/2 and JNK activation, which suppresses Bcl-2 expression .
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- HY-116615
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Methyl cerebronate
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Biochemical Assay Reagents
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Others
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Methyl (+/-)-2-hydroxytetracosanoate, a hydroxylated fatty acid methyl ester, has been found in mature and immature strawberry homogenates, Pseudosuberites and S. massa sponges, sediment samples from Hani River and Lake Kivu, and aerial parts of Escherichia coli found in. sun mirror.
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- HY-B0928R
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Homomenthyl salicylate (Standard)
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Biochemical Assay Reagents
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Others
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Homosalate (Standard) is the analytical standard of Homosalate. This product is intended for research and analytical applications. Homosalate (Homomenthyl salicylate) is an organic compound used as a sunscreen to filter UV rays and protect the skin from sun damage. Homosalate has anti-inflammatory activity .
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- HY-A0087
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Biochemical Assay Reagents
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Others
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Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .
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- HY-121432
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Others
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Others
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Kitol is peptide used for after-sun repair cosmetics. The dominant degradation reaction for vitamin A derivatives is heat-induced formation of kitols, i.e., dimers or higher oligomers. Vitamin A esters are used as a model system to evaluate microcalorimetry as a tool for monitoring the stability of heat-sensitive substances .
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- HY-B1234
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Octyl methoxycinnamate
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Androgen Receptor
Estrogen Receptor/ERR
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Others
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Octinoxate (Octyl methoxycinnamate) is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
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- HY-B1234A
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(E)-Octyl methoxycinnamate
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Estrogen Receptor/ERR
Androgen Receptor
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Endocrinology
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(E)-Octinoxate is the isomer of Octinoxate (HY-B1234). Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
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- HY-N3950
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Microtubule/Tubulin
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Cancer
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Glochidiol is an orally active tubulin polymerization inhibitor with an IC50 of 2.76 μM. Glochidiol shows anti-cancer activity .
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- HY-N3305
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Megastigma-7-en-3,5,6,9-tetraol
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Others
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Inflammation/Immunology
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Megastigm-7-ene-3,5,6,9-tetraol (Megastigma-7-en-3,5,6,9-tetraol) is a diterpenoid analogue in the aerial parts of Isodon melissoides. Megastigm-7-ene-3,5,6,9-tetraol is also in Vigna luteola and has anti-inflammatory bioactivity .
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- HY-A0067S
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RAR/RXR
Apoptosis
Autophagy
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Neurological Disease
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Oxybenzone-d5 is the deuterium labeled Oxybenzone[1]. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[2][3][4].
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- HY-A0067R
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Benzophenone 3 (Standard)
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RAR/RXR
Autophagy
Apoptosis
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Neurological Disease
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Oxybenzone (Standard) is the analytical standard of Oxybenzone. This product is intended for research and analytical applications. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .
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- HY-N2466
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MT-I; [Nle4,D-Phe7]-α-MSH
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Melanocortin Receptor
|
Neurological Disease
Cancer
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Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction .
|
-
Cat. No. |
Product Name |
Type |
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- HY-116615
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Methyl cerebronate
|
Biochemical Assay Reagents
|
Methyl (+/-)-2-hydroxytetracosanoate, a hydroxylated fatty acid methyl ester, has been found in mature and immature strawberry homogenates, Pseudosuberites and S. massa sponges, sediment samples from Hani River and Lake Kivu, and aerial parts of Escherichia coli found in. sun mirror.
|
Cat. No. |
Product Name |
Target |
Research Area |
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- HY-N2466
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MT-I; [Nle4,D-Phe7]-α-MSH
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Melanocortin Receptor
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Neurological Disease
Cancer
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Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N3181
-
-
-
- HY-N3798
-
-
-
- HY-N3321
-
-
-
- HY-N3400
-
-
-
- HY-N1258
-
-
-
- HY-N10643
-
-
-
- HY-N9017
-
-
-
- HY-N10078
-
-
-
- HY-133223
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-
-
- HY-N1256
-
-
-
- HY-N11050
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-
-
- HY-N9983
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-
-
- HY-N8646
-
-
-
- HY-N7521
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-
-
- HY-N2969
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-
-
- HY-N9930
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-
-
- HY-N3322
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-
-
- HY-N11049
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-
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- HY-N2504
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-
-
- HY-N12746
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-
-
- HY-N7463
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-
-
- HY-N3428
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-
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- HY-30151
-
-
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- HY-135737
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-
-
- HY-N11544
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-
-
- HY-N11548
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-
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- HY-N3828
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-
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- HY-B1234
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-
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- HY-N3950
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-
-
- HY-N3305
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Megastigma-7-en-3,5,6,9-tetraol
|
other families
Classification of Application Fields
Terpenoids
Sesquiterpenes
Source classification
Plants
Disease Research Fields
Inflammation/Immunology
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Others
|
Megastigm-7-ene-3,5,6,9-tetraol (Megastigma-7-en-3,5,6,9-tetraol) is a diterpenoid analogue in the aerial parts of Isodon melissoides. Megastigm-7-ene-3,5,6,9-tetraol is also in Vigna luteola and has anti-inflammatory bioactivity .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0928S
-
|
Homosalate-d4 is the deuterium labeled Homosalate. Homosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage.
|
-
-
- HY-A0067S
-
|
Oxybenzone-d5 is the deuterium labeled Oxybenzone[1]. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[2][3][4].
|
-
Cat. No. |
Product Name |
Application |
Reactivity |
-
- HY-P82277
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Sun1; UNC84A
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WB, IHC-P, ICC/IF, FC
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Human |
-
- HY-P82280
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FRIGG; UNC84B
|
WB, IHC-P, ICC/IF, FC
|
Human, Mouse, Rat |
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